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2%), lunesta vs ambien treato lunesta sleep lunesta vs trazodone lunesta urinary retention side effects hallucinations (2% vs .
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Nine patients on LUNESTA (3%) discontinued treatment lunesta due to an adverse reaction compared to 3 patients on placebo (2%) .
In studies in which eszopiclone (2 to 300 mg/kg/day) eszopiclone zopiclone difference lunesta for long term use lunesta food lunesta lunesta heartburn was orally administered to young rats from weaning through sexual maturity, neurobehavioral impairment (altered auditory startle response) and reproductive toxicity (adverse effects on male reproductive organ weights and histopathology) were observed at doses ≥ 5 mg/kg/day .
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The no-effect dose (2 mg/kg) was associated with plasma exposures (AUC) for eszopiclone and metabolite (S)-desmethylzopiclone [(S)-DMZ] approximately 2 times plasma exposures in humans at the maximum recommended dose (MRHD) in adults (3 lunesta mg/day) .
When eszopiclone (doses from 1 to 50 mg/kg/day) was orally lunesta administered to young dogs from weaning through sexual maturity, neurotoxicity (convulsions) was observed at doses ≥ 5 mg/kg/day .
Hepatotoxicity (elevated liver enzymes and hepatocellular vacuolation and Reference lunesta toxicity lunesta most common side effects eszopiclone long term use lunesta and xanax high ID: 3506700 degeneration) and reproductive toxicity (adverse effects on male reproductive organ weights and histopathology) were noted at dose ≥10 mg/kg/day .

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